NCT02021045

Cerebral Microembolism During Hemodialysis

Quantity, Quality and Laterality of Cerebral Microembolism During Veno-Venous Hemodialysis.

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 40 (actual)
• Sponsor: Medical University of Vienna · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

There is increasing evidence that renal replacement therapy (= continuous veno-venous hemodialysis) generates cerebral microembolism which is detectable on transcranial Doppler ultrasound. The aim of this study is to monitor patients with transcranial Doppler under two conditions: during hemodialysis and in a hemodialysis-free interval (in each period cerebral embolic load is detected during 30 minutes). The study hypothesis is that during hemodialysis the cerebral embolic load is significantly higher than in the hemodialysis-free interval.

Conditions

• Complication of Dialysis
• Thrombus Due to Renal Dialysis Device, Implant, or Graft
• Cerebral Embolism

Interventions

Type	Name	Description
DEVICE	Renal hemodialysis (Fresenius 2008K, Bad Homburg, Germany)	Renal replacement therapy is frequently used in patients with renal failure in order to eliminate substances obligatory excreted by the urine.

Timeline

• Start date: 2013-09-01
• Primary completion: 2015-11-01
• Completion: 2016-03-01
• First posted: 2013-12-27
• Last updated: 2016-03-04

Locations

1 site across 1 country: Austria