Clinical Trials Directory

Trials / Completed

CompletedNCT02019394

Absolute Bioavailability of Lu AE58054 in Healthy Subjects

Interventional, Open-label Study Investigating the Absolute Bioavailability of Lu AE58054 After Multiple Oral Dosing and a Single Radio-labelled Intravenous Micro-dose as Well as the Contribution of Cytochrome P450 2D6 to the Exposure of Lu AE58054 in Healthy Subjects

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
10 (actual)
Sponsor
H. Lundbeck A/S · Industry
Sex
All
Age
21 Years – 55 Years
Healthy volunteers
Accepted

Summary

To determine the absolute bioavailability of the Lu AE58054 tablet formulation at steady state

Conditions

Interventions

TypeNameDescription
DRUGLu AE58054Oral dosing: 90 mg Lu AE58054 as a single dose once and after a 3 days washout period, once daily for 7 days. Intravenous dosing: 90 μg/not more than (NMT) 1000 nCi/37 kBq 14C-Lu AE58054 for intravenous infusion once on Day 10.

Timeline

Start date
2013-12-01
Primary completion
2014-02-01
First posted
2013-12-24
Last updated
2014-03-21

Locations

1 site across 1 country: United Kingdom

Source: ClinicalTrials.gov record NCT02019394. Inclusion in this directory is not an endorsement.