NCT02018952

Ultrasonography Assessment of Septic Arthritis on Native Joint

Ultrasonography Assessment of Septic Arthritis on Native Joint: a Descriptive, Exploratory, Prospective, Multicentric Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 28 (actual)
• Sponsor: Nantes University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim of this trial is to study the interest of ultrasonography among patients with septic arthritis. Currently, ultrasonography is useful for detecting small fluid effusions, for examining otherwise inaccessible joints, such as the hip and for helping the joint aspiration. Accurate assessment of disease activity and joint damage in septic arthritis is important for monitoring treatment efficiency and for prediction of the outcome of the disease. Nowadays, magnetic resonance imaging (MRI) provides better resolution than radiography or tomography for the detection of joint effusion and for differentiation between bone and soft tissue infectious. The sensibility is reported to be nearly 100% with a specificity of more than 75%. However, MRI is expensive and not rapidly accessible. Therefore, ultrasonography, a non invasive, painless, inexpensive, and non radiating exam can be used to assess the presence and extent of inflammation, destruction, and tissue response. The objective is to describe, using ultrasonography, the abnormalities joint structure influenced the septic arthritis evolution and prognosis. The investigators hope, at the end of this study, to evaluate ultrasonography interest in septic arthritis and to establish ultrasonography prognosis factors to predict treatment efficiency and functional outcome.

Conditions

• Septic Arthritis

Interventions

Type	Name	Description
OTHER	Ultrasonography assessment	All patients will be seen at day 0, day 4, day 15 and at 3 months. These visits are usually programmed. Only monitoring ultrasonography, a non invasive exam, and self-administered questionnaires will be made, additional to standard exams for all patients included (no control group). Day 0 : * Information of patient and no opposition getting * Clinical exam * Laboratory tests * Radiography of the targeted joint * Ultrasonography of the targeted joint and controlateral joint (about 20 minutes) Day 4 : * Clinical exam * Laboratory tests * Ultrasonography of the targeted joint and controlateral joint (about 20 minutes) Day15 : * Clinical exam * Laboratory tests * Ultrasonography of the targeted joint and controlateral joint (about 20 minutes) M3 : * Clinical exam * Laboratory tests * Radiography of the targeted joint * Ultrasonography of the targeted joint and controlateral joint (about 20 minutes) * Functional outcome

Timeline

• Start date: 2014-01-01
• Primary completion: 2015-07-01
• Completion: 2015-07-01
• First posted: 2013-12-23
• Last updated: 2016-03-25

Locations

3 sites across 1 country: France