NCT02018783

Single Application of Desensitizing Pastes as Dentin Sensitivity Treatment

Clinical Evaluation of the Effectiveness of Immediate Relief Obtained With Desensitizing Creams - A Controlled, Randomized, Triple Masked, Split-Mouth Clinical Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 138 (actual)
• Sponsor: Federal University of São Paulo · Academic / Other
• Sex: All
• Age: 22 Years – 48 Years
• Healthy volunteers: Accepted

Summary

The aim of this study was to evaluate the efficacy of three desensitizing toothpastes for immediate and intermediate-term relief of CDH, when compared with a control toothpaste. One hundred and thirty-eight hypersensitive teeth were diagnosed and randomized into four groups according to the therapeutic agent of each desensitizing cream tested: 1) strontium acetate and calcium carbonate, 2) calcium carbonate and arginine 8%, 3) calcium phosphate nanoparticles and 4) a control toothpaste. The desensitizing creams were applied according to the manufacturer's instructions. Cervical dentin hypersensitivity was assessed at baseline, immediately, 24 hours and 30 days after the treatment. Cold and evaporative tests were used to assess the sensitivity level.

Conditions

• Dentine Hypersensitivity

Interventions

Type	Name	Description
PROCEDURE	Colgate	Slow-speed handpiece with a Robson brush for 3 seconds by repeating the procedure
PROCEDURE	Sensodyne	Digital application for 60 seconds.
PROCEDURE	Nano P	Slow-speed handpiece with a Robson brush for 10 seconds
PROCEDURE	Cocorico	Digital application for 60 seconds

Timeline

• Start date: 2013-04-01
• Primary completion: 2013-08-01
• Completion: 2013-08-01
• First posted: 2013-12-23
• Last updated: 2013-12-23

Locations

1 site across 1 country: Brazil