NCT02016651

Positioning and Gastric Aspiration in Ventilated Premature Infants

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 34 (actual)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 3 Days – 28 Days
• Healthy volunteers: Not accepted

Summary

Gastro-esophageal reflux and aspiration is a common problem in premature infants receiving mechanical ventilation. Pepsin measured in tracheal aspirate (TA) emerged as a specific marker for aspiration. The objective of this study is to examine if TA pepsin will change when ventilated premature infants are positioned in two different positions; on their back vs. on their right side.

Conditions

• Respiratory Aspiration of Gastric Contents

Interventions

Type	Name	Description
BEHAVIORAL	Right side position	Enrolled infants are positioned on their back or right side. Tracheal aspirate is assessed for pepsin concentration as an index of aspiration.

Timeline

• Start date: 2012-01-01
• Primary completion: 2013-07-01
• Completion: 2013-12-01
• First posted: 2013-12-20
• Last updated: 2013-12-20

Locations

1 site across 1 country: Egypt