NCT02014818

Multicenter Comparison of Early and Late Vascular Responses to Everolimus-eluting Cobalt-CHromium Stent

Multicenter Comparison of Early and Late Vascular Responses to Everolimus-eluting Cobalt-CHromium Stent and Platelet AggregatioN Studies In Patients With Stable Angina Managed as Elective Case : MECHANISM-Elective

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 104 (actual)
• Sponsor: Kobe University · Industry
• Sex: All
• Age: 20 Years – 84 Years
• Healthy volunteers: Not accepted

Summary

To treat patients with stable coronary artery disease, elective percutaneous coronary intervention (PCI) will be performed with the use of an everolimus-eluting cobalt- chromium stent (everolimus-eluting stent: EES, Xience Prime, Xpedition), which is the current standard drug-eluting stent (DES). Vascular responses at the site of stent placement will be evaluated by optical coherence tomography (OCT) at 1 or 3 months and at 12 months after stent placement, along with observation of changes over time in the target vessel. The relationships between OCT findings and the time course of platelet aggregation and between OCT findings and the occurrence of major cardio- cerebrovascular events will also be elucidated.

Conditions

• Coronary Artery Disease

Interventions

Type	Name	Description
DEVICE	CoCr-EES

Timeline

• Start date: 2014-01-01
• Primary completion: 2017-12-31
• Completion: 2018-12-31
• First posted: 2013-12-18
• Last updated: 2017-10-18

Locations

1 site across 1 country: Japan