NCT02014805

Postoperative Conformal Radiotherapy for Stage II-III B Type Thymoma

A Multi-institutional, Randomized Controlled Trial of Postoperative Conformal Radiotherapy for Stage II-III B Type Thymoma

• Status: Unknown
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 210 (estimated)
• Sponsor: Chinese Academy of Medical Sciences · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether postoperative conformal radiotherapy are effective in the treatment of Masaoka stage II-III B type thymoma.

Detailed description

The role of postoperative radiotherapy in thymoma is controversial. Some retrospective studies were for the radiotherapy, but others were against. However, more inherent biases existed in these trials. Resection, Masaoka stage and pathology were widely accepted as the prognostic factors for thymoma. Furthermore, the frequency of local failure after radical resection was still high in Masaoka stage II-III B type thymoma. With the conformal technique appearing, conformal radiotherapy can escalate the dose without increasing the risk of normal tissue toxicities.

Conditions

• Thymoma

Interventions

Type	Name	Description
RADIATION	radiotherapy	postoperative conformal radiotherapy for Masaoka stage II-III B type thymoma

Timeline

• Start date: 2013-07-01
• Primary completion: 2021-07-01
• Completion: 2022-07-01
• First posted: 2013-12-18
• Last updated: 2020-07-16

Locations

1 site across 1 country: China