Trials / Completed
CompletedNCT02008734
Randomized Phase II Study to Assess PD 0332991 in Breast Cancer
Randomized Short-term Pre-surgical Study to Assess the Effects of PD 0332991 in Early Breast Cancer Patients
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 132 (actual)
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris · Academic / Other
- Sex
- Female
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This is a Phase II study trying to identify whether short term treatment with PD0332991 yields anti-proliferative response -defined by a low level of Ki67 expression (IHC) at surgery- or induces senescence as determined by SABG expression (IHC) in tumors from patients with early breast cancer non-candidates for neoadjuvant hormonotherapy or chemotherapy, as compared to no treatment.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | PD0332991 |
Timeline
- Start date
- 2014-01-01
- Primary completion
- 2016-01-01
- Completion
- 2016-01-01
- First posted
- 2013-12-11
- Last updated
- 2016-06-09
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT02008734. Inclusion in this directory is not an endorsement.