Clinical Trials Directory

Trials / Terminated

TerminatedNCT02007720

Efficacy, Safety and Tolerability of Sexelaxin When Added to Standard Therapy in AHF

A Multicenter, Randomized, Double-blind, Placebo Controlled Phase III Study to Evaluate the Efficacy, Safety and Tolerability of Serelaxin When Added to Standard Therapy in Acute Heart Failure Patients

Status
Terminated
Phase
Phase 3
Study type
Interventional
Enrollment
876 (actual)
Sponsor
Novartis Pharmaceuticals · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of the study was to evaluate the efficacy, safety and tolerability of intravenous infusion of serelaxin, when added to standard therapy, in acute heart failure (AHF) patients.

Conditions

Interventions

TypeNameDescription
DRUGSerelaxinIntravenous infusion
DRUGPlaceboIntravenous infusion
OTHERStandard of CareTherapyThis treatment can include but is not limited to intravenous and/or oral diuretics, ACE inhibitors/angiotensin receptor antagonists, β blockers, and aldosterone receptor antagonists, etc.

Timeline

Start date
2014-03-12
Primary completion
2017-03-27
Completion
2017-06-16
First posted
2013-12-11
Last updated
2019-08-02
Results posted
2019-08-02

Locations

132 sites across 11 countries: China, India, Japan, Jordan, Lebanon, Malaysia, Philippines, Singapore, South Korea, Taiwan, Thailand

Source: ClinicalTrials.gov record NCT02007720. Inclusion in this directory is not an endorsement.