Trials / Recruiting
RecruitingNCT02007356
A Study to Assess Safety and Feasibility of Direct Infusions of Donor-derived Virus-specific T-cells in Recipients of Hematopoietic Stem Cell Transplantation With Post-transplant Viral Infections Using the Cytokine Capture System®
A Phase I/II Single-center Study to Assess Safety and Feasibility of Direct Infusions of Donor-derived Virus-specific T-cells in Recipients of Hematopoietic Stem Cell Transplantation With Post-transplant Viral Infections Using the Cytokine Capture System®
- Status
- Recruiting
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- Sponsor
- University Hospital, Basel, Switzerland · Academic / Other
- Sex
- All
- Age
- 18 Years – 65 Years
- Healthy volunteers
- Not accepted
Summary
To assess the feasibility of donor-derived interferon (IFN)-γ positive select-ed virus-specific T-cells using the cytokine capture system® (CCS) and the safety of subsequent infusion in recipients of hematopoietic stem cell transplantation (HSCT) with treatment refractory post-transplant viral infections. The CCS has already been successfully used in clinical studies in Germany and United Kingdom (UK).
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | IFN-γ positive selected T-cells |
Timeline
- Start date
- 2014-12-01
- Primary completion
- 2026-12-01
- Completion
- 2026-12-01
- First posted
- 2013-12-10
- Last updated
- 2025-03-20
Locations
1 site across 1 country: Switzerland
Source: ClinicalTrials.gov record NCT02007356. Inclusion in this directory is not an endorsement.