NCT02006563

Metabolic Tumor Volumes in Radiation Treatment of Primary Brain Tumors

Evaluation of Metabolic Tumor Volumes in Radiation of Primary Brain Tumors

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 22 (actual)
• Sponsor: University of Miami · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

* Metabolic Tumor Volume (MTV), identified by Magnetic Resonance Spectroscopic Imaging (MRSI) is different from the Clinical Target Volume (CTV) used for radiation dose delivery in the treatment of brain tumors. * If MTV \> CTV, the investigators hypothesize that the difference in volumes (cc) is related to worse clinical outcome. Furthermore, in case of local recurrence, the lesion is located in the MTV area that is outside of the CTV. * Alternatively, if CTV \> MTV, then the difference in volumes is related to higher treatment toxicity.

Detailed description

Metabolic Tumor Volume (MTV), identified by Magnetic Resonance Spectroscopic Imaging (MRSI) is different from the Clinical Target Volume (CTV) used for radiation dose delivery in the treatment of brain tumors. * If MTV \> CTV, the investigators hypothesize that the difference in volumes (cc) is related to worse clinical outcome. Furthermore, in case of local recurrence, the lesion is located in the MTV area that is outside of the CTV. * Alternatively, if CTV \> MTV, then the difference in volumes is related to higher treatment toxicity.

Conditions

• Brain Tumor
• Glioblastoma Multiforme

Timeline

• Start date: 2011-06-08
• Primary completion: 2016-01-01
• Completion: 2017-07-01
• First posted: 2013-12-10
• Last updated: 2017-10-24

Locations

1 site across 1 country: United States