NCT02006407

A Pilot Study to Evaluate Neurocognitive Injury and Longitudinal Changes in White Matter During Radiation Therapy in Children With Primary Brain Tumors

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 5 (actual)
• Sponsor: University of Michigan Rogel Cancer Center · Academic / Other
• Sex: All
• Age: 6 Years – 21 Years
• Healthy volunteers: Not accepted

Summary

This is a pilot study to assess the changes in white matter, in the brain, in response to radiation therapy and correlate these changes with later declines in cognitive function.

Conditions

• Brain Tumor, Primary

Interventions

Type	Name	Description
RADIATION	Cranial Radiotherapy	Standard cranial radiotherapy administered dependent upon patient and brain tumor type.
DEVICE	MRI with Diffusion Tensor Imaging (DTI)	Magnetic Resonance Imaging (MRI) with Diffusion Tensor Imaging (DTI)
BEHAVIORAL	Neuro-cognitive Testing (CogState)	CogState is a computerized software testing system that offers various cognitive assessments based traditional expansive neurocognitive tests.

Timeline

• Start date: 2013-06-01
• Primary completion: 2015-08-01
• Completion: 2015-12-01
• First posted: 2013-12-10
• Last updated: 2016-12-30
• Results posted: 2016-10-27

Locations

1 site across 1 country: United States