NCT02004015

Assessment Study of the Effect of NMBA on Bowel Peristalsis

Effect of an Induction Dose of Non Depolarizing Neuro Muscular Blocking Agents (NMBA) on Ultrasound Bowel Peristalsis.

• Status: Terminated
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: Fondation Ophtalmologique Adolphe de Rothschild · Network
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Phase III prospective randomised study : curare vs placebo, comparing bowel peristalsis (abdominal echography) in the first minutes of after general anesthesia induction. Primary End Point: proportion of patients with a score of motion = 0

Detailed description

Primary End Point Proportion of patients with a score of motion = 0 Secondary End Point Time at which thumb adductor twitch measurement disappears (3rd consecutive measure with a twitch at 0) Mean minimal twitch measurement for those patients in who twitch measurement does not disappear Concordance study between twitch measurement and bowel peristalsis XML File Identifier: 1vUwHz2uUXeSc7soLu1cQwRAfcM= Page 15/24 ultrasound score.

Conditions

• Physiopathology

Interventions

Type	Name	Description
DRUG	injection of placebo	0.5 mg/kg milligram(s)/kilogram
DRUG	injection of NMBA

Timeline

• Start date: 2013-11-01
• Primary completion: 2015-04-01
• First posted: 2013-12-06
• Last updated: 2017-02-13

Locations

1 site across 1 country: France