NCT02002806

Surgery Plus Celiac Nerve Block for Long-term Pancreatic Cancer Pain Control

A Randomized Controlled Trial of Intraoperative Chemical Splanchnicectomy for Patients With Resected Pancreatobiliary Malignancies

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 150 (actual)
• Sponsor: Indiana University · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

This is a randomized study of surgery plus chemical nerve block versus surgery plus placebo for pain control in subjects with pancreatic cancer.

Detailed description

Thi is a study of pain control in subjects undergoing surgery for pancreatic or bile duct cancer. Subjects undergoing surgery will be randomized to surgery plus celiac plexus neurolysis with ethanol injection versus surgery plus placebo injection. Subjects will be followed every three months for survivorship or death to assess pain, quality of life measures, and narcotic pain control usage. The primary endpoint of pain control will be determined at one year post surgery. Subjects are not required to undergo any additional diagnostic testing procedures that are not part of their routine follow-up care.

Conditions

• Pancreas Cancer
• Biliary Tract Cancer

Interventions

Type	Name	Description
OTHER	Alcohol Injection	Celiac plexus neurolysis by alcohol injection
OTHER	Placebo Injection

Timeline

• Start date: 2012-01-01
• Primary completion: 2018-12-01
• Completion: 2019-06-01
• First posted: 2013-12-06
• Last updated: 2019-08-16

Locations

1 site across 1 country: United States