NCT02002754

The Effect of Bronchodilator on Eosinophilic Bronchitis and Cough Variant Asthma

Randomised, Open-label, Parallel-group Study of the Response to Bronchodilator Treatment in Subjects With Eosinophilic Bronchitis and the Mechanism of Varied Responses to Bronchodilator Treatment.

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 45 (estimated)
• Sponsor: The First Affiliated Hospital of Guangzhou Medical University · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

This study aim is to observe the response to Bambuterol Hydrochloride tablets treatment in subjects with eosinophilic bronchitis . The investigators hypothesize: A few of subjects with EB have some responses to Bambuterol Hydrochloride tablets therapy. Most of subjects with CVA respond well to Bambuterol Hydrochloride tablets therapy

Detailed description

Study groups: 45 patients with chronic cough will be collected and two groups will formed based on diagnosis as follows: Group 1: EB group The patients with eosinophilic bronchitis received Bambuterol Hydrochloride tablets 10mg Q24 for three days . Group 2: CVA group The patients with cough variant asthma received Bambuterol Hydrochloride tablets 10mg Q24 for three days . Observe the response to Bambuterol Hydrochloride tablets treatment three days later and compare the effective rate of patients with EB and CVA. Then the study will be over.

Conditions

• Eosinophilic Bronchitis
• Cough Variant Asthma

Interventions

Type	Name	Description
DRUG	Bambuterol Hydrochloride tablets	Bambuterol Hydrochloride tablets(10mg) 3 tablets qd for three days(swallowed by warm water at 0.5-1h after each meal)

Timeline

• Start date: 2012-06-01
• Primary completion: 2014-03-01
• Completion: 2014-03-01
• First posted: 2013-12-06
• Last updated: 2013-12-06

Locations

1 site across 1 country: China