Clinical Trials Directory

Trials / Terminated

TerminatedNCT02002377

Intravitreal Aflibercept in Wet Age Related Macular Degeneration Patients With an Incomplete Response to Routine Ranibizumab Injections

The SHIFT-2 Study: Use of Intravitreal Aflibercept in Wet Age Related Macular Degeneration (AMD) Patients With an Incomplete Response to Routine Ranibizumab Injections

Status
Terminated
Phase
Phase 4
Study type
Interventional
Enrollment
23 (actual)
Sponsor
Unity Health Toronto · Academic / Other
Sex
All
Age
51 Years
Healthy volunteers
Not accepted

Summary

SHIFT-2 is a national, multi-center, non-randomized, open label trial of aflibercept in patients with wet age related macular degeneration who have incomplete response with routineranibizumab treatment.

Conditions

Interventions

TypeNameDescription
DRUGAfliberceptAflibercept 2 mg (0.05 mL or 50 microliters) will be administered by intravitreal injection every 4 weeks for the first 8 weeks, followed by 2 mg (0.05 mL) via intravitreal injection once every 8 weeks for 36 weeks

Timeline

Start date
2014-04-17
Primary completion
2017-02-21
Completion
2017-02-21
First posted
2013-12-05
Last updated
2018-04-24

Locations

9 sites across 1 country: Canada

Source: ClinicalTrials.gov record NCT02002377. Inclusion in this directory is not an endorsement.