Trials / Completed
CompletedNCT02001935
Association Between CytochromeP4501A2 and CytochromeP4502E1 Gene Polymorphisms and Metabolism of Theophylline
Association Between CytochromeP4501A2(CYP1A2) and CytochromeP4502E1(CYP2E1) Gene Polymorphisms and Metabolism of Theophylline in a Chinese Population
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 102 (actual)
- Sponsor
- Zhujiang Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
The aim of this study is to determine whether common CYP1A2 and CYP2E1 gene polymorphisms effect metabolism of theophylline in chronic obstructive pulmonary disease patients.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | theophylline | After oral theophylline 200mg per day for two weeks,bood sample will be collected for determining plasma concentrations of theophylline and it's metabolites and the genotypes of CYP1A2 and CYP2E1 |
Timeline
- Start date
- 2013-09-01
- Primary completion
- 2014-07-01
- Completion
- 2014-07-01
- First posted
- 2013-12-05
- Last updated
- 2014-08-20
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT02001935. Inclusion in this directory is not an endorsement.