Clinical Trials Directory

Trials / Completed

CompletedNCT02001688

Phase II, Safety and Efficacy Study of Kamada-alpha-1-antitrypsin (AAT) for Inhalation"

Phase II, Double-Blind, Placebo-Controlled Study to Explore the ELF and Plasma Concentration as Well as Safety of Inhaled Alpha-1 Antitrypsin in Alpha-1 Antitrypsin Deficiency Subjects

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
36 (actual)
Sponsor
Kamada, Ltd. · Industry
Sex
All
Age
18 Years – 65 Years
Healthy volunteers
Not accepted

Summary

To evaluate different doses of "Kamada-AAT for Inhalation" on the levels of alpha 1-proteinase inhibitor and other analytes in epithelial lining fluid (ELF) and serum and to assess the safety of the treatment in subjects with AAT Deficiency.

Conditions

Interventions

TypeNameDescription
DRUGKamada-AAT for Inhalation, 80mg
DRUGPlacebo
DRUGKamada-AAT for Inhalation, 160mg

Timeline

Start date
2014-04-01
Primary completion
2016-02-01
Completion
2016-05-01
First posted
2013-12-05
Last updated
2020-01-18
Results posted
2020-01-18

Locations

2 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT02001688. Inclusion in this directory is not an endorsement.