Trials / Completed
CompletedNCT02001389
Study of EVP-6308 to Assess the Dose- and Concentration-dependent Displacement of [18F]MNI-659 by EVP-6308
A Phase 1, Open-Label, Multiple Ascending Dose, [18F]MNI-659 PET-Imaging Study to Evaluate PDE10A Occupancy After Dosing With EVP-6308 in Healthy Subjects
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 14 (actual)
- Sponsor
- FORUM Pharmaceuticals Inc · Industry
- Sex
- All
- Age
- 18 Years – 50 Years
- Healthy volunteers
- Accepted
Summary
This is an open-label, single-arm, multiple ascending dose Phase I study to assess the dose- and concentration-dependent displacement of \[18F\]MNI-659 \[a PET tracer targeting phosphodiesterase 10 (PDE10)\] by EVP-6308.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | EVP-6308 | Arms 1, 2, 3, 4 |
Timeline
- Start date
- 2013-10-01
- Primary completion
- 2014-06-01
- First posted
- 2013-12-04
- Last updated
- 2014-10-10
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT02001389. Inclusion in this directory is not an endorsement.