NCT02000973

Effects of Epidural Local Anesthetics on Propofol Induction

Effects of Thoracic Epidural Anesthesia With Different Local Anesthetics on Propofol Induction

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: First Hospital of China Medical University · Academic / Other
• Sex: All
• Age: 45 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The investigators designed a prospective, randomized, placebo-controlled study to determine whether thoracic epidural anesthesia(TEA) with different local anesthetics has different influences on the propofol dose during induction.

Conditions

• General Anesthesia
• Propofol Target-controlled Infusion
• Thoracic Epidural Anesthesia

Interventions

Type	Name	Description
DRUG	Lidocaine	General anesthesia combined with thoracic epidural 1% lidocaine
DRUG	Bupivacaine	General anesthesia combined with thoracic epidural 0.25% bupivacaine
DRUG	Ropivacaine	General anesthesia combined with thoracic epidural 0.3% ropivacaine
DRUG	Normal Saline	General anesthesia combined with thoracic epidural 0.9% normal saline

Timeline

• Start date: 2013-11-01
• Primary completion: 2014-01-01
• Completion: 2014-03-01
• First posted: 2013-12-04
• Last updated: 2014-05-16
• Results posted: 2014-05-16