Clinical Trials Directory

Trials / Completed

CompletedNCT02000219

Study to Evaluate the Efficacy and Safety of Oxabact (OC5) in Primary Hyperoxaluria Patients Who Are on Dialysis

A Phase 2 Open-label Multi-centre Study to Evaluate the Efficacy and Safety of Oxabact® to Reduce Plasma Oxalate in Subjects With Primary Hyperoxaluria Who Are on Dialysis

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
12 (actual)
Sponsor
OxThera · Industry
Sex
All
Age
2 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine if Oxalobacter formigenes is effective at lowering plasma oxalate levels in patients with primary hyperoxaluria who are on dialysis.

Conditions

Interventions

TypeNameDescription
BIOLOGICALOxalobacter formigenesThe dose will be (not less than) NLT ≥1E+09 colony forming units (CFU) twice daily. The dose (an enteric-coated capsule) will be administered orally with breakfast and dinner.

Timeline

Start date
2014-05-19
Primary completion
2020-01-29
Completion
2020-01-29
First posted
2013-12-04
Last updated
2022-01-10
Results posted
2021-12-09

Locations

1 site across 1 country: Germany

Source: ClinicalTrials.gov record NCT02000219. Inclusion in this directory is not an endorsement.