NCT02000063

Australian Trial in Acute Hepatitis C Recall Study

Long-term Outcomes Following Treatment of Recently Acquired Hepatitis C Virus Infection.

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 50 (actual)
• Sponsor: Kirby Institute · Other Government
• Sex: All
• Age: 16 Years
• Healthy volunteers: Not accepted

Summary

A single long-term follow up assessment of an established multi-centre, prospective longitudinal cohort study of patients for clinical, psychosocial, immunovirological outcomes 4 to 8 years after previous treatment for recently acquired hepatitis C virus infection.

Detailed description

The study aims are: 1. To evaluate the effect of successful prior treatment or spontaneous clearance of recently acquired HCV infection on long-term quality of life, social functioning, injecting behaviour, mental health and liver health. 2. To assess the incidence of HCV re-infection following prior treatment induced clearance or spontaneous clearance of recently acquired chronic HCV infection. 3. To determine predictors of HCV re-infection following recently acquired HCV infection treatment. 4. To determine frequency and predictors of new mixed and superinfections in ATAHC subjects with persistent viraemia. 5. To add to a tissue repository of serum and PBMCs from well-characterised patients treated for recently acquired HCV infection to allow future examination of the role of other variables that may potentially impact on the prognosis and outcomes of early HCV treatment.

Conditions

• Acute Hepatitis C

Timeline

• Start date: 2012-08-01
• Primary completion: 2014-03-01
• Completion: 2014-03-01
• First posted: 2013-12-03
• Last updated: 2014-10-01

Locations

3 sites across 1 country: Australia