NCT01998620

Efficacy and Safety of S-adenosyl-L-methionine in Treatment of Chronic Hepatitis B Patients With Cholestasis

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 240 (estimated)
• Sponsor: Zhejiang Hisun Pharmaceutical Co. Ltd. · Industry
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

This is an evaluation of adenosine methionine for treatment of chronic hepatitis b patients with cholestasis efficacy and safety of multicenter, randomized, open label clinical trial.

Detailed description

evaluation of adenosine methionine for treatment of chronic hepatitis b patients with cholestasis efficacy and safety

Conditions

• Hepatitis B
• Cholestasis

Interventions

Type	Name	Description
DRUG	Ademetionine 2	Ademetionine 1000mg ivgtt qd with general antiviral treatment for 2 weeks, then Ademetionine 500mg po bid with general antiviral treatment for 8 weeks
DRUG	Ademetionine 1	Ademetionine 2000mg ivgtt qd with general antiviral treatment for 2 weeks, then Ademetionine 1000mg bid po with general antiviral treatment for 8 weeks
DRUG	Ademetionine 3	no treatment for 2 weeks, then Ademetionine 1000mg bid po with general antiviral treatment for 8 weeks

Timeline

• Start date: 2013-11-01
• Primary completion: 2015-05-01
• Completion: 2015-05-01
• First posted: 2013-12-02
• Last updated: 2014-05-29

Locations

1 site across 1 country: China