NCT01998334

Continuous Blood Purification for Regulation of Early Inflammatory Response In Severe Acute Pancreatitis

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Ruijin Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Systemic Inflammatory response syndrome(SIRS) is common in patients with severe acute pancreatitis (SAP) in early stage. Continuous Blood Purification (CBP), especially Continuous Veno-Venous Hemofiltration(CVVH) is proved to have an important role in SAP patients to control SIRS. But the detail treatment for this is controversial. In this study, the investigators aim to evaluate the different effects of three kinds of treatment protocols which is CVVH 6h,continuous venovenous hemodiafiltration(CVVHDF) 6h,CVVH 10h for first three days in SAP patients. Compare the vital sign, SIRS parameters, and others between these three groups. This study will try to find a better way for CBP in patients with SAP

Detailed description

Condition Severe Acute Pancreatitis Intervention CVVH 6 hours for first three days CVVH 10 hours for first three days CVVHDF 6 hours for first three days All therapeutic volume is 45ml/kg.h, Device: Braxter HF 1200

Conditions

• Acute Pancreatitis

Interventions

Type	Name	Description
OTHER	CVVH 6h	CVVH 6h for first three days
OTHER	CVVH 10h	CVVH 10h for first three days
OTHER	CVVHDF 6h	CVVHDF 6h for first three days

Timeline

• Start date: 2012-07-01
• Primary completion: 2015-12-01
• Completion: 2016-12-01
• First posted: 2013-11-28
• Last updated: 2013-11-28

Locations

1 site across 1 country: China