NCT01993849

Use of N-Acetylcysteine (NAC) in Fingernail Biting

A Randomized Placebo-controlled Trial of N-Acetylcysteine in Onychophagia

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 23 (actual)
• Sponsor: Kevin Gray, MD · Academic / Other
• Sex: All
• Age: 18 Years – 30 Years
• Healthy volunteers: Not accepted

Summary

To conduct a pilot randomized placebo-controlled feasibility trial of N-acetylcysteine (NAC) in onychophagia, preliminarily assessing the tolerability and effects of this pharmacotherapy on young adults who bite their fingernails. It is proposed that NAC will help decrease fingernail biting.

Detailed description

This is a proof-of-concept pilot placebo-controlled trial of N-acetylcysteine (NAC) in young people who bite fingernails. The primary interest is in assessing the feasibility of conducting this line of research, while preliminarily exploring potential effects on nail biting, as measured by nail length.

Conditions

• Onychophagia

Interventions

Type	Name	Description
DRUG	N-Acetylcysteine (NAC)	This is the medication N-acetylcysteine (NAC)
OTHER	Placebo	Placebo, designed to match in appearance to NAC

Timeline

• Start date: 2013-10-01
• Primary completion: 2015-06-01
• Completion: 2015-06-01
• First posted: 2013-11-25
• Last updated: 2018-10-03
• Results posted: 2018-10-03

Locations

1 site across 1 country: United States