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Trials / Completed

CompletedNCT01993186

Phase 2 Study of Triheptanoin (UX007) for the Treatment of Glucose Transporter Type 1 Deficiency Syndrome (Glut1 DS)

A Randomized, Double-blind, Placebo-controlled, Parallel-group, Study to Assess the Safety and Efficacy of UX007 in Subjects With Glucose Transporter Type 1 Deficiency Syndrome

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
36 (actual)
Sponsor
Ultragenyx Pharmaceutical Inc · Industry
Sex
All
Age
1 Year – 100 Years
Healthy volunteers
Not accepted

Summary

The primary objectives of the study are to evaluate the efficacy of UX007 compared to placebo as measured by the reduction from randomization to Week 8 in frequency of seizures and to evaluate the safety of UX007 via adverse event (AE) rates, laboratory values, and electrocardiogram (ECG).

Conditions

Interventions

TypeNameDescription
DRUGUX007oral liquid
DRUGPlacebooral liquid

Timeline

Start date
2014-02-28
Primary completion
2017-09-20
Completion
2017-09-20
First posted
2013-11-25
Last updated
2020-06-19
Results posted
2020-05-29

Locations

14 sites across 7 countries: United States, Australia, France, Israel, Italy, Spain, United Kingdom

Source: ClinicalTrials.gov record NCT01993186. Inclusion in this directory is not an endorsement.

Phase 2 Study of Triheptanoin (UX007) for the Treatment of Glucose Transporter Type 1 Deficiency Syndrome (Glut1 DS) (NCT01993186) · Clinical Trials Directory