Clinical Trials Directory

Trials / Completed

CompletedNCT01991860

US Phase III Study of APD421 in PONV

Randomized, Double-blind, Placebo-controlled Phase III Study of APD421 (Amisulpride for IV Injection) as Prophylaxis Against Post-operative Nausea and Vomiting

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
364 (actual)
Sponsor
Acacia Pharma Ltd · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

A comparison of the efficacy of APD421 and placebo in the prevention of PONV in patients at moderate-to-high risk of PONV.

Conditions

Interventions

TypeNameDescription
DRUGAPD421- Amisulpride for IV injectionAPD421 ( Amisulpride) at 5mg given by single intravenous (IV) administration, by slow push over one minute, at induction of anaesthesia
DRUGPlaceboMatching Placebo given by single intravenous (IV) administration, by slow push over one minute, at induction of anaesthesia

Timeline

Start date
2013-08-01
Primary completion
2014-01-01
Completion
2014-01-01
First posted
2013-11-25
Last updated
2019-02-12
Results posted
2018-09-06

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT01991860. Inclusion in this directory is not an endorsement.