NCT01991535

Response to NonInvasive Mechanical Ventilation According to the Breathing Pattern

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether breathing pattern (specifically the inspiratory time/total respiratory cycle value) has an influence over the response to the noninvasive mechanical ventilation.

Detailed description

Breathing pattern will be analyzed along the adaptation to 3 different NonInvasive-Mechanical-Ventilation modes (controlled mode, spontaneous mode and placebo mode or simulator).

Conditions

• Neuromuscular Disorders
• Chest Wall Disorders
• Obesity Hypoventilation Syndrome (OHS)

Interventions

Type	Name	Description
DEVICE	Spontaneous Ventilation Mode	Respiratory rate and duration of inspiration are controlled by the patient. Device model: Stellar 150® (ResMed, Australia).
DEVICE	Controlled Ventilation Mode	Ventilator maintains the positive end-expiratory pressure until the patient inspires. At that point, the ventilator reaches the support pressure in a predetermined time. The patient fixes the respiratory rate and the duration of inspiration, triggering all the cycles. Device model: Stellar 150® (ResMed, Australia).
DEVICE	Simulator Ventilation Mode	Ventilator maintains a continuous positive airway pressure during the entire cycle. Device model: Stellar 150® (ResMed, Australia).

Timeline

• Primary completion: 2016-12-01
• First posted: 2013-11-25
• Last updated: 2024-03-21

Locations

1 site across 1 country: Spain