Clinical Trials Directory

Trials / Completed

CompletedNCT01991327

Assessment of Drug-Drug Interactions of Androxal With Cytochrome P450 Isoenyzmes in Healthy Males

AN OPEN-LABEL, MULTIPLE DOSE STUDY TO ASSESS THE DRUG-DRUG INTERACTIONS OF ANDROXAL WITH CYTOCHROME P450 ISOENZYMES IN HEALTHY MALE SUBJECTS

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
30 (actual)
Sponsor
Repros Therapeutics Inc. · Industry
Sex
Male
Age
18 Years – 60 Years
Healthy volunteers
Accepted

Summary

The primary objective of this study is to assess the drug-drug interactions of Androxal with cytochrome P450 isoenzymes, CYP1A2, CYP2C8, CYP2C9, CYP2C19, CYP2D6, and CYP3A4 in healthy male subjects administered 25 mg Androxal once daily for 3 days. Secondly, the safety and tolerability of Androxal will be determined in healthy male subjects administered Androxal 25 mg daily for 3 days.

Conditions

Interventions

TypeNameDescription
DRUGAndroxal
DRUGPlacebo

Timeline

Start date
2014-05-01
Primary completion
2014-07-01
Completion
2014-07-01
First posted
2013-11-25
Last updated
2014-08-11

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT01991327. Inclusion in this directory is not an endorsement.

Assessment of Drug-Drug Interactions of Androxal With Cytochrome P450 Isoenyzmes in Healthy Males (NCT01991327) · Clinical Trials Directory