NCT01986530

Circulating Levels of Irisin in Healthy Young Subjects

Circulating Irisin in Healthy Young Men and Women and Correlation With Lean Body Mass, Fat Mass and Adipocytokines. Circadian and Seasonal Variation and the Effect of Food Intake and Exercise

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 122 (actual)
• Sponsor: 424 General Military Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 25 Years
• Healthy volunteers: Accepted

Summary

Irisin, a newly discovered myokine induced in exercise, has potential effects in stimulating adipose tissue browning, fighting obesity and diabetes. No prior study has reported on the role of circulating irisin in healthy individuals in correlation with lean and fat body mass. Furthermore, the circadian and seasonal variation of irisin is largely unknown.

Detailed description

The main aims of this prospective study will be to investigate: 1) circulating irisin levels in healthy, young men and women according to their lean and fat mass; 2) the circadian variations of irisin levels; 3) the seasonal variations of irisin levels.

Conditions

• Healthy Subjects

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Boost	After an overnight fast, blood samples will be obtained before as well as 30 min after standardized mixed meal ingestion
OTHER	Aerobic exercise	After an overnight fast and rest, blood samples will be obtained before as well as 30 min after aerobic exercise

Timeline

• Start date: 2013-11-01
• Primary completion: 2015-01-01
• Completion: 2015-01-01
• First posted: 2013-11-18
• Last updated: 2015-01-22

Locations

1 site across 1 country: Greece