NCT01985204

Iodine Supplementation in Obesity

Assessment of the Improvement of the Cardiovascular Risk Profile in Obese Women After Correction of Iodine Deficiency

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 162 (actual)
• Sponsor: Swiss Federal Institute of Technology · Academic / Other
• Sex: Female
• Age: 20 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The study hypothesis is that iodine supplementation will lower serum TSH and leptin concentrations and thereby improve the lipid and glucose profile.

Detailed description

The study will be a double blind, placebo controlled intervention study in obese women living in the Atlas foot mountains in Morocco, an iodine deficient area. Eligible subjects will be randomized into intervention and control group and will receive the respective supplement for 6 months. At baseline, midpoint and endpoint anthropometric as well as metabolic profile will be assessed. A health questionnaire will further be administered monthly when the tablets for the following month are distributed. Urine samples to determine iodine status will also be collected monthly.

Conditions

• Iodine Deficiency
• Subclinical Hypothyroidism

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Iodine tablet	Iodine tablets containing 200 ug iodine as potassium iodate
DIETARY_SUPPLEMENT	Placebo tablet	Placebo tablet without iodine

Timeline

• Start date: 2013-11-01
• Primary completion: 2014-06-01
• Completion: 2014-07-01
• First posted: 2013-11-15
• Last updated: 2014-07-30

Locations

2 sites across 1 country: Morocco