NCT01983943

Olive Oil and Cardiovascular Health

Effects of Hydroxytyrosol on Vascular Health

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Mayo Clinic · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to conduct a double-blind, randomized controlled trial (RCT), to determine if six month supplementation of olive oil can improve the health of the blood vessels and improve long term health of the heart and blood vessels, in patients requiring percutaneous coronary intervention (PCI).

Conditions

• Cardiovascular Disease
• Endothelial Function

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Hydroxytyrosol, the active ingredient in olive oil.	A 40mg capsule will be taken once daily for 6 months.
DIETARY_SUPPLEMENT	Placebo	A 40mg placebo will be taken once per day for 6 months.
BEHAVIORAL	Nutrition counseling	Nutrition counseling on eating a healthy diet will be offered once at baseline.
DEVICE	Endopat	An endopat test will be administered twice, once and baseline and once after 6 months of supplementation, to test endothelial function. This is a non-invasive test that takes about 15 minutes.

Timeline

• Start date: 2013-08-01
• Primary completion: 2014-07-01
• Completion: 2014-07-01
• First posted: 2013-11-14
• Last updated: 2015-06-03

Locations

1 site across 1 country: United States