Trials / Completed
CompletedNCT01983904
DBS for Treatment Resistant Depression
Therapeutic Brain Stimulation for Refractory Depression
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 22 (actual)
- Sponsor
- University of Calgary · Academic / Other
- Sex
- All
- Age
- 20 Years – 70 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to examine the effects of sub-callosal cingulate (SCC) deep brain stimulation (DBS) in patients with treatment resistant depression (TRD). The working hypotheses are that long pulse-width DBS applied to the SCC region will lead to improvements in TRD patients, and specific neuroimaging biomarkers will correlate with response to DBS; the functional recovery will be enhanced with concurrent cognitive behavioural therapy (CBT).
Detailed description
The aim is to collect data on prediction, optimization and augmentation of DBS for TRD and develop tools for DBS surgery. It is a biological pilot study designed to provide informative data for future work.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | deep brain stimulation with short & long pulse width | surgical implantation for bilateral electrodes and stimulation using short and long pulse width |
Timeline
- Start date
- 2013-08-01
- Primary completion
- 2017-12-01
- Completion
- 2018-03-01
- First posted
- 2013-11-14
- Last updated
- 2019-04-18
Locations
1 site across 1 country: Canada
Source: ClinicalTrials.gov record NCT01983904. Inclusion in this directory is not an endorsement.