NCT01982760

DDAVP in the Reduction of Post-operative Ecchymosis in Rhinoplasty

A Prospective Randomized Trial for the Use of DDAVP in the Reduction of Post-operative Ecchymosis in Rhinoplasty.

• Status: Terminated
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 14 (actual)
• Sponsor: University Hospitals Cleveland Medical Center · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

This is study looking at the use of a medication, Desmopressin acetate (DDAVP), to reduce bleeding, swelling, and bruising in patients undergoing cosmetic nose surgery. DDAVP is a drug used in patients with bleeding disorders. It works by activating molecules in the blood stream called platelets that promote clotting. In the study, participants who are have cosmetic nose surgery (rhinoplasty) will be randomly assigned to receive or not receive medication. Photographs taken before and shortly after surgery will be evaluated for the amount of bruising and swelling. Patients with heart, lung, kidney, or liver problems are not eligible to participate.

Conditions

• Postoperative Ecchymosis

Interventions

Type	Name	Description
DRUG	DDAVP	Patients Receiving DDAVP prior to operation

Timeline

• Start date: 2013-12-01
• Primary completion: 2015-06-25
• Completion: 2015-06-25
• First posted: 2013-11-13
• Last updated: 2023-08-16
• Results posted: 2023-08-16

Locations

1 site across 1 country: United States