NCT01982136

Functional Outcome of Urethral Reconstructive Surgery

Prospective Long-term Single Center Cohort Study Assessing Functional Outcome of Urethral Reconstructive Surgery

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 175 (actual)
• Sponsor: Universitaire Ziekenhuizen KU Leuven · Academic / Other
• Sex: Male
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The analysis of the long-term outcomes and quality-of-life parameters after urethral reconstruction surgery.

Detailed description

Urethroplasty is the surgical repair of a urethral stricture. Depending on the location, severity and length of the stricture, various techniques can be performed. The first procedure consists of the excision of the stenotic segment and end-to-end anastomosis. Other procedures consist of widening the urethra with buccal mucosa as free graft or with vascularized (genital) skin flaps. The results of these techniques have been described in prospective cohort studies, but to date there is little good data about the functional outcome and quality-of-life with longer follow-up after this surgery. The purpose of this study is to prospectively follow patients for functional outcome parameters and quality-of-life to obtain long-term information concerning these surgeries.

Conditions

• Urethral Stricture

Interventions

Type	Name	Description
PROCEDURE	end-to-end urethroplasty
PROCEDURE	substitution urethroplasty (buccal mucosa)
PROCEDURE	substitution urethroplasty (pedicled skin flap)

Timeline

• Start date: 2009-08-01
• Primary completion: 2019-10-01
• Completion: 2019-10-01
• First posted: 2013-11-13
• Last updated: 2019-10-29

Locations

1 site across 1 country: Belgium