NCT01981460

PhotoDynamic Therapy for Line Infection Prevention (PLIP): Pilot Study on Healthy Volunteers.

PhotoDynamic Therapy for Line Infection Prevention (PLIP): Pilot Study on Normal Volunteers

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Massachusetts General Hospital · Academic / Other
• Sex: All
• Age: 21 Years – 60 Years
• Healthy volunteers: Accepted

Summary

We are evaluating the effect of methylene blue and visible light activation on the microbiome of the skin.

Detailed description

Antiseptics are routinely utilized to prevent infections of vascular catheters. We are evaluating the addition of methylene blue and light activation on skin to determine whether this inexpensive and non-toxic treatment can decrease skin pathogens and prevent blood stream infections of long-term vascular catheters. This is a pilot study of normal volunteers to determine the effect on the microbiome of the addition of methylene blue and light activation on antiseptic-treated skin.

Conditions

• Light; Therapy, Complications

Interventions

Type	Name	Description
PROCEDURE	Methylene blue and light treatment	Methylene blue and light treatment for 17 minutes are done twice over 1 week intervals.

Timeline

• Start date: 2013-05-01
• Primary completion: 2013-06-01
• Completion: 2013-07-01
• First posted: 2013-11-11
• Last updated: 2013-11-11