NCT01976442

Use of Saline-Washed Platelet and Red Cell Transfusions in Adult Acute Leukemia

Impact of Washed Transfusions in Adult Patients With Acute Myeloid or Lymphoid Leukemia

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 100 (actual)
• Sponsor: University of Rochester · Academic / Other
• Sex: All
• Age: 50 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether a novel standard of care protocol, washing red cell and platelet transfusions for younger patients with acute leukemia, has yielded improved clinical outcomes at Strong Memorial Hospital (Rochester, New York, USA). This standard of care was implemented based upon an earlier randomized trial (BMC Blood Disorders. 2004 Dec 10;4(1):6) The comparator will be historical controls from the medical literature.

Detailed description

The purpose of this study is to determine whether a novel standard of care protocol, washing red cell and platelet transfusions for younger patients with acute leukemia, has yielded improved clinical outcomes at Strong Memorial Hospital (Rochester, New York, USA). This standard of care was implemented based upon an earlier randomized trial (BMC Blood Disorders. 2004 Dec 10;4(1):6) The comparator will be historical controls from the medical literature. Key outcomes will be treatment related mortality (deaths at 30, 60 and 100 days) and three year survival.

Conditions

• Leukemia, Myeloid, Acute
• Leukemia, Lymphoblastic, Acute

Timeline

• Start date: 2011-03-01
• Primary completion: 2016-11-01
• Completion: 2016-11-01
• First posted: 2013-11-05
• Last updated: 2017-04-11
• Results posted: 2017-04-11

Locations

1 site across 1 country: United States