NCT01974583

Wound-healing Improvement by Resurfacing Split-Thickness Skin Donor Sites With Thin Split-thickness Grafting

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 192 (actual)
• Sponsor: Tang-Du Hospital · Academic / Other
• Sex: All
• Age: 5 Years – 56 Years
• Healthy volunteers: Not accepted

Summary

Split-thickness skin grafting remains fundamental treatment of patients with deep burns and other traumatic injuries. However, the split-thickness skin graft (STSG) donor site dressing has been controversial until now. Our study here aimed to assess patient comfort and wound-healing efficacy with the application of thin split-thickness grafting on STSG donor sites.

Detailed description

Background：Split-thickness skin grafting remains fundamental treatment of patients with deep burns and other traumatic injuries. However, the split-thickness skin graft (STSG) donor site dressing has been controversial until now. Our study here aimed to assess patient comfort and wound-healing efficacy with the application of thin split-thickness grafting on STSG donor sites. Methods: 192 consecutive patients undergoing split-thickness skin grafting were included in the study and the participants were randomly divided into three groups: Group A was regrafted with thin STSG, while, Group B and Group C were covered with the occlusive hydrocellular dressing and paraffin gauze, respectively. The three groups were compared regarding to the time of epithelialization, pain sensed by the patients and the scar formation.

Conditions

• Skin Graft Disorder
• Disorder of Skin Donor Site
• Wound Healing Disturbance of

Interventions

Type	Name	Description
PROCEDURE	regrafted with thin split-thickness skin graft	Group A (the treatment group) were regrafted with thin split-thickness skin graft
PROCEDURE	covered with the occlusive hydrocellular dressing	group B covered with the occlusive hydrocellular dressing (Allevyn Adhesive, Smith \& Nephew)
PROCEDURE	covered with paraffin gauze	Group C covered with paraffin gauze

Timeline

• Start date: 2002-01-01
• Primary completion: 2010-12-01
• Completion: 2013-03-01
• First posted: 2013-11-01
• Last updated: 2013-11-01