NCT01969877

A Study of Cisplatin Plus Radiotherapy Compared to Cetuximab Plus Radiotherapy in Locally Advanced Head and Neck Cancer.

A Randomized Multicenter Phase III Study of Cisplatin Plus Radiotherapy Compared to Cetuximab Plus Radiotherapy in Locally Advanced Head and Neck Cancer.

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 298 (actual)
• Sponsor: Lund University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The primary endpoint in this study is to investigate if there is a difference in overall survival in patients with locally advanced head and neck cancer, randomized to either radiotherapy and cetuximab or radiotherapy and cisplatin. A second randomization is performed in patients with T3-T4 tumors; allocated radiotherapy either 68.0 Gy or 73.1 Gy.

Conditions

• Locally Advanced Head and Neck Cancer

Interventions

Type	Name	Description
DRUG	cetuximab
DRUG	cisplatin

Timeline

• Start date: 2013-11-01
• Primary completion: 2018-04-01
• Completion: 2018-04-01
• First posted: 2013-10-25
• Last updated: 2020-09-02

Locations

9 sites across 1 country: Sweden