NCT01969110

Additional Effects of Perioperative Immunonutrition in Patients Undergoing Pancreaticoduodenectomy

Additional Effects of Perioperative Immunonutrition on Th1/Th2 Differentiation in Patients Undergoing Pancreaticoduodenectomy

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Chiba University · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to investigate whether perioperative immunonutrition has additional effects on cell-mediated immunity in patients undergoing pancreaticoduodenectomy.

Detailed description

The investigators reported that perioperative immunonutrition had no additional effects compared with preoperative immunonutrition in patients underwent colorectal surgery (Braga M, Gianotti L, Vignali A, Carlo VD. Preoperative oral arginine and n-3 fatty acid supplementation improves the immunometabolic host response and outcome after colorectal resection for cancer. Surgery. 2002; 132:805-14, PMID: 12464864). Object of this study is to investigate the additional effects of perioperative immunonutrition on cell-mediated immunity and incidence of infectious complication after pancreaticoduodenectomy.

Conditions

• Pancreatic Tumor
• Bile Duct Tumor

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Oral IMPACT	Oral IMPACT enriched with arginine, omega-3 fatty acids, and RNA by enteral feeding after surgery

Timeline

• Start date: 2013-01-01
• Primary completion: 2015-09-01
• Completion: 2015-09-01
• First posted: 2013-10-25
• Last updated: 2013-10-25

Locations

1 site across 1 country: Japan