Clinical Trials Directory

Trials / Completed

CompletedNCT01968980

A 52 Week Study To Assess The Use Of Bococizumab (PF-04950615; RN316) In Subjects With Heterozygous Familial Hypercholesterolemia

A 52 Week, Phase 3 Double-blind, Randomized, Placebo-controlled, Parallel-group Study To Assess The Efficacy, Safety And Tolerability Of Pf-04950615 In Subjects With Heterozygous Familial Hypercholesterolemia

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
370 (actual)
Sponsor
Pfizer · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This is a multicenter, randomized study in subjects with heterozygous familial hypercholesterolemia receiving highly effective statins to assess the safety, efficacy and tolerability of Bococizumab (PF-04950615; RN316) to lower LDL-C.

Conditions

Interventions

TypeNameDescription
DRUGBococizumab (PF-04950615;RN316)150 mg every 2 weeks, subcutaneous injection, 12 months
OTHERPlacebosubcutaneous injection every 2 weeks for 12 months

Timeline

Start date
2013-10-23
Primary completion
2016-04-15
Completion
2016-04-15
First posted
2013-10-24
Last updated
2017-06-26
Results posted
2017-05-19

Locations

88 sites across 11 countries: United States, Bulgaria, Canada, Finland, Italy, Netherlands, Norway, Poland, South Africa, Spain, United Kingdom

Source: ClinicalTrials.gov record NCT01968980. Inclusion in this directory is not an endorsement.