NCT01963520

Prosthetic Hip Infections: Prospective Study

Prospective Study of Patients Treated for Prosthetic Hip Infection and Followed for at Least 2 Years

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 347 (actual)
• Sponsor: Groupe Hospitalier Diaconesses Croix Saint-Simon · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Data from large prospective cohort studies of prosthetic joint infections are lacking. Aim of this study: analyzing prospectively the incidence of reinfection in patients with prosthetic hip infections who underwent surgery and received antibiotic therapy. Hypothesis: to confirm in a large group that the incidence of reinfection after excision -synovectomy in acute prosthesis hip infection is 30% and 15% for chronic infection after exchange arthroplasty (one or two stage exchange).

Detailed description

Aim of the study: to analyze the incidence of reinfection in patients with prosthetic hip infection who underwent surgery and received antibiotic therapy Methods: prospective cohort study in a French referral center for osteoarticular infections from November 2002 to March 2010. Population * all patients who consented to participate in the study with prosthetic hip infections treated by: * debridement-synovectomy for acute infection or with one-stage or two-stage * exchange arthroplasty or resection arthroplasty for chronic infection * antibiotic therapy Outcome: * Follow-up: minimum of 2 years * Events monitored: reinfection including relapse and new infection, joint revision for mechanical reasons, prosthetic hip infection related and non-related deaths

Conditions

• Hip Prosthesis Infection

Timeline

• Start date: 2002-08-02
• Primary completion: 2010-03-01
• Completion: 2015-09-10
• First posted: 2013-10-16
• Last updated: 2018-02-14

Locations

1 site across 1 country: France