NCT01963442

Short Duration Treatment of Non-severe Community Acquired Pneumonia

A Non-Inferiority, Multicentered, Controlled, Randomized, Double Blinded Study Investigating the Antibiotic Treatment Duration (3-day Versus 8-day) for Subjects Admitted to Emergency Services With Acute Non-severe Community Acquired Pneumonia (CAP)

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 310 (estimated)
• Sponsor: Versailles Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

To investigate the non inferiority of a short lasting antibiotic treatment (3 days) when compared to a long lasting antibiotic treatment (8 days), at Day 15 after the beginning of treatment in terms of clinical efficacy, in adults admitted to emergency services for a non severe Community Acquired Pneumonia (PAC), who responded well to 3 days of beta-lactamin treatment (3GC or A/AC).

Conditions

• Community Acquired Pneumonia

Interventions

Type	Name	Description
RADIATION	Chest X-ray	at Day 0, Day 30 and relapse
BIOLOGICAL	blood sampling /Cell Counts/ C reactive protein (CRP)/Biochemistry
DRUG	Augmentin	2 tablets 3 times a day for 5 days from Day 3
DRUG	Placebo (for Augmentin)	2 tablets 3 times a day for 5 days from Day 3
DRUG	Beta-Lactams	administered from Day 0 to Day 3

Timeline

• Start date: 2013-11-01
• Primary completion: 2018-06-01
• Completion: 2018-06-01
• First posted: 2013-10-16
• Last updated: 2017-08-14

Locations

20 sites across 1 country: France