NCT01963299

Clonidine - Ropivacaine in Peribulbar Anesthesia

Prospective Randomised Double-blind Study to Compare Ropivacaine 10mg/mL Alone Versus Ropivacaine 10mg/mL Associated With Clonidine 1µg/kg for Peribulbar Anesthesia in Posterior Eye Surgery

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Centre Hospitalier Universitaire Dijon · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is a study conducted in 60 patients, randomly assigned to one of two groups of 30: the first will receive ropivacaine alone and the second will receive the association ropivacaine/clonidine. The aim of the study is to prove that the association of Clonidine with Ropivacaine is more effective than ropivacaine alone for locoregional anaesthesia of the eye for retinal surgery. The principal interest of this association of drugs is that it procures faster and longer anaesthesia of the eye with less ropivacaine (therefore fewer injections). This provides greater comfort to the patient during and after the intervention.

Conditions

• Indication for Surgery of the Posterior Segment Under Locoregional Anaesthesia

Interventions

Type	Name	Description
DRUG	5 ml Ropivacaine 10% + physiological saline
DRUG	5 ml Ropivacaine 10% + Clonidine 1 µg/kg

Timeline

• Start date: 2013-08-16
• Primary completion: 2013-10-07
• Completion: 2013-10-07
• First posted: 2013-10-16
• Last updated: 2019-01-10

Locations

1 site across 1 country: France