NCT01962324

Dose Escalation With SIB to Intraprostatic/Lymphatic GTV in High Risk Prostate Cancer

Phase 2 Study of High Risk Prostatae Cancer Treated With Dose-escalated Simultaneous Integrated Boost to Prostate and Lymph Node GTV

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 85 (actual)
• Sponsor: Umeå University · Academic / Other
• Sex: Male
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

A single arm phase 2 study to study the outcome of dose-escalation with simultaneous integrated boost to intraprostatic lesion and positive lymph nodes. Prostate cancer patients with high risk of lymph node metastasis or oligo positive nodes in true pelvic area can be included. The boost volumes will be outlined by usin PET-CT and MRI data. Our hypothesis is that we will have fewer relapses in this very high risk patient group compared to matched historical controls with acceptable side effects.

Conditions

• Prostatic Neoplasms
• Lymphatic Metastasis

Interventions

Type	Name	Description
RADIATION	SIB Dose-Escalation Radiotherapy

Timeline

• Start date: 2015-03-01
• Primary completion: 2023-05-09
• Completion: 2023-05-09
• First posted: 2013-10-14
• Last updated: 2024-03-01

Locations

1 site across 1 country: Sweden