NCT01962116

Citrate Versus Heparin for the Lock of Non-tunneled Hemodialysis Catheters in Patients Hospitalised in ICU

Citrate Versus Heparin for the Lock of Non-tunneled Hemodialysis Catheters in Patients Hospitalised in ICU = Multicentre, Controlled, Randomised Superiority Trial

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 405 (actual)
• Sponsor: Centre Hospitalier Universitaire Dijon · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

After obtaining written informed consent and inclusion, patients will be randomised into 2 groups for the type of dialysis catheter lock: * The first group will have a citrate lock * The second group will have a heparin lock Patients will be stratified according to the centre and type of Renal Replacement Therapy (RRT) continuous or intermittent. The daily surveillance of patients will not be different from the usual surveillance of patients on Renal Replacement Therapy. The hemodialysis catheters used will be specific Renal Replacement Therapy catheters. The decision to withdraw the catheter will be made by the investigator and based on clinical criteria (complications related to the catheter, termination of Renal Replacement Therapy…)

Conditions

• Patients With Acute Renal Insufficiency

Interventions

Type	Name	Description
DRUG	Citrate 4%
DRUG	unfractionated heparin

Timeline

• Start date: 2013-06-14
• Primary completion: 2016-04-01
• Completion: 2016-12-31
• First posted: 2013-10-14
• Last updated: 2026-02-09

Locations

1 site across 1 country: France