NCT01961505

Topical Compound Tripterygium Wilfordii Hook F for Patients With Active Rheumatoid Arthritis

A Randomized Controlled Study to Determine the Effects and Safety of Topical Compound Tripterygium Wilfordii Hook F in Patients With Active Rheumatoid Arthritis.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 70 (actual)
• Sponsor: Guang'anmen Hospital of China Academy of Chinese Medical Sciences · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Rheumatoid Arthritis (RA) is an autoimmune disease that results in a chronic inflammatory disorder that may affect many synovial joints, and may cause serious disability. It has been confirmed that Tripterygium wilfordii Hook F has effects of anti-inflammatory, immunosuppressive and cartilage protection. This is a prospective randomized controlled study to evaluated the efficacy and safety of external application with compound Tripterygium wilfordii Hook F in treating of patients with rheumatoid arthritis (RA).

Conditions

• Active Rheumatoid Arthritis

Interventions

Type	Name	Description
DRUG	Topical compound tripterygium	Topical compound tripterygium was applied for the pain and swollen joints on non-woven fabric for 1 hour, twice per day.
DRUG	Placebo	The topical placebo recipe composes viscous agent which matches by the sucrose, and the usage and dosage were the same as the topical compound tripterygium group.

Timeline

• Start date: 2011-10-01
• Primary completion: 2015-09-01
• Completion: 2016-12-01
• First posted: 2013-10-11
• Last updated: 2017-04-28