Clinical Trials Directory

Trials / Completed

CompletedNCT01956422

Continuous Positive Airway Pressure (CPAP) for Preventing Respiratory Failure After Laparoscopic Radical Prostatectomy

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
48 (actual)
Sponsor
ASST Fatebenefratelli Sacco · Academic / Other
Sex
Male
Age
18 Years – 70 Years
Healthy volunteers
Not accepted

Summary

Aim of this study is verify if postoperative CPAP after laparoscopic prostatectomy may reduce the impact of postoperative respiratory failure, defined as occurrence of hypoxemia (PaO2\<60 mmHg) and/or reduction of Forced Expiratory Volume in 1 second (FEV1) beyond 70% of basal value.

Detailed description

Laparoscopic radical prostatectomy (LRP) is a wide used, well tolerated procedure. However, the general anesthesia, the need for pneumoperitoneum and Trendelenburg position may have detrimental effects on both pulmonary volumes and mechanics, and they may increase the risk of postoperative respiratory failure (PORF). Continuous positive airway pressure (CPAP) improves oxygenation and reduces the rate of re-intubation in the presence of PORF. The aim of our study is to investigate postoperative respiratory function and the likely benefits of the use of CPAP, compared with Venturi mask in terms of prevention of post-operative hypoxaemia and worsening of lung spirometry. CPAP is delivered with "CASTAR" Helmet by StarMed.

Conditions

Interventions

TypeNameDescription
DEVICEContinuous Positive Airway Pressure(CPAP)
DEVICEVenturi Mask FiO2 40%

Timeline

Start date
2013-08-01
Primary completion
2014-07-01
Completion
2014-07-01
First posted
2013-10-08
Last updated
2014-07-11

Locations

1 site across 1 country: Italy

Source: ClinicalTrials.gov record NCT01956422. Inclusion in this directory is not an endorsement.