NCT01951300

68Ga-Citrate PET of Healthy Volunteers

68Ga-Citrate Positron Emission Tomography (PET) of Healthy Volunteers

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 6 (actual)
• Sponsor: Turku University Hospital · Other Government
• Sex: Male
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This study investigates whole-body distribution kinetics of intravenously administered Gallium-69 (68Ga) citrate by positron emission tomography (PET)/computed tomography (CT). Thereafter, radiation dosimetry of 68Ga-citrate PET/CT will be determined.

Detailed description

Six healthy male volunteers are recruited in this study. Gallium-68 citrate radiopharmaceutical is intravenously injected as a bolus and whole-body distribution kinetics are studied by dynamic whole-body positron emission tomography/computed tomography. During imaging, serial venous blood samples are drawn, plasma is separated and radioactivity is measured by gamma counter. Immediately after imaging session, urine is voided and radioactivity is measured by gamma counting. As a final point, radiation dosimetry due to single Gallium-68 citrate injection is determined.

Conditions

• Healthy

Interventions

Type	Name	Description
OTHER	Gallium-68 citrate	Single intravenous bolus injection of 200 MBq of Gallium-68 citrate radiopharmaceutical

Timeline

• Start date: 2013-09-01
• Primary completion: 2015-10-01
• Completion: 2015-10-01
• First posted: 2013-09-26
• Last updated: 2015-11-04

Locations

1 site across 1 country: Finland