NCT01951079

Intra Amniotic Injection of DIGOXIN for Feticide in Second Trimester Termination of Pregnancy

The Safety and Outcome of Intra-amniotic DIGOXIN Injection for Feticide Prior to Second Trimester Abortion

• Status: Unknown
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Meir Medical Center · Academic / Other
• Sex: Female
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

In second trimester abortion above 22 weeks the investigators usually inject intra-cardiac Kcl for feticide. Digoxin intra-amniotic injection has been described in the literature in doses of 1-1.5 mg. with a success rate of about 80%, and up to 24 weeks. Our aim in this study is to investigate the safety and success rate of 1.5-2 mg. digoxin, intra-amniotic up to 30 weeks pregnancy .

Detailed description

* The digoxin will be injected intra-amniotic with U.S guided, trying to avoid any placental passage or intravascular injection / * Any patient will have prior to the procedure a full examination including E.C.G and cardiac clearance.

Conditions

• Arrhythmia
• ECG Changes
• Hypotension

Interventions

Type	Name	Description
DRUG	Intra-amniotic injection of DIGOXIN

Timeline

• Start date: 2013-11-01
• Primary completion: 2014-11-01
• Completion: 2014-12-01
• First posted: 2013-09-26
• Last updated: 2013-09-26

Locations

2 sites across 1 country: Israel